NEET UG · Biology · Molecular Basis of Inheritance

Human Genome Project: NEET previous year questions

6 questions in ten years of NEET, in 5 of 10 papers. Pattern: Every year. Here is how it is asked and which ideas come back.

Asked in 10 years: 6; about 0.6 per paper
Years asked: 5/10; last asked 2025
Chance of a question next paper: 50%; historical rate, how we compute it
Weighted estimate: 0.6; model; history: 0.6 a paper on average, typically 0–1

Key findings

01
Asked in 5 of 10 papers, 6 questions in all: #132 of 204 topics by ten-year total. It comes back every 1.5 years on average. Last asked in 2025.
02
100% of its questions since 2018 tested an idea never asked before; none repeated an idea from the year before.
03
No idea in this topic has been asked twice: every question tested something new.
04
NEET has asked 4 of the 78 ideas in this topic; 72 have never been asked, directly or indirectly.
05
Mostly asked as one-line MCQ (100%); 67% easy, 0% hard, and down from 0.7 to 0.3 questions a paper since 2024.

Questions per year

Up to 2023: 0.7; per paper
Since 2024: 0.3; -0.3
Usual gap: 1.5 yrs; between papers asking it
Swing: ±0.6; questions, year to year

How it is asked

Difficulty, format and skill

Across all 6 questions on Human Genome Project since 2017.

Difficulty

QUESTIONS

Easy4 · 67%
Medium2 · 33%
Hard0 · 0%

Format

One-line MCQ · 6 Q100%

Skill tested

Recall · 6 Q100%

Repeats

New idea, or one asked before?

Each column is a paper. Blue questions tested an idea NEET had not asked before; navy ones went back to an idea from an earlier paper. 2017 is the first paper, so everything in it counts as new.

’17’18’19’20’21’22’23’24’25’26

Idea asked for the first time
Idea asked in an earlier paper

Coverage of the topic

NEET has asked 4 of the 78 ideas in this topic. 72 have never been asked yet.

Asked directly4 · 5%
Touched inside another question2 · 3%
Never asked72 · 92%

Ideas come from Lumi’s syllabus map of NCERT. A never-asked idea is not a safe skip: most new questions come from exactly these.

Drill down

Idea, year, question

Every idea NEET tested in this topic, with its ten papers. Open one to read the questions.

ideaAskedShareYears’17’18’19’20’21’22’23’24’25’26

1 · 17%17%1/10
- 2023 · Q104
  Expressed Sequence Tags (ESTs) refers to
  easyOne-line MCQNew idea
1 · 17%17%1/10
1 · 17%17%1/10
1 · 17%17%1/10
1 · 17%17%1/10
1 · 17%17%1/10

Squares are the ten papers, 2017 to 2026; darker means more questions. Share is of the level above.

Ideas

Every idea inside this topic

6 different ideas were tested; none came more than once. Salient Features of HGP is the foundation for 30 other ideas in the syllabus.

Salient Features of HGP1×
definition recall
One-line MCQ · 6% next · foundation for 30
Definition of Expressed Sequence Tags1×
definition recall
One-line MCQ · 4% next
DNA Polymorphism1×
definition recall
One-line MCQ · 4% next
Sequence Annotation Definition1×
identify methodology from description
One-line MCQ · 4% next
DNA Fingerprinting and VNTRs1×
identify term describing dna region
One-line MCQ · 4% next
ESTs vs Sequence Annotation1×
definition recall
One-line MCQ · 4% next · foundation for 24

Idea	Times	Format	Chance next	Foundation for
Salient Features of HGPdefinition recall	1	One-line MCQRecall	6%	30 ideas
Definition of Expressed Sequence Tagsdefinition recall	1	One-line MCQRecall	4%	–
DNA Polymorphismdefinition recall	1	One-line MCQRecall	4%	–
Sequence Annotation Definitionidentify methodology from description	1	One-line MCQRecall	4%	–
DNA Fingerprinting and VNTRsidentify term describing dna region	1	One-line MCQRecall	4%	–
ESTs vs Sequence Annotationdefinition recall	1	One-line MCQRecall	4%	24 ideas

Chance next is the historical rate at which an idea with this record came back in the following paper. It is low for every idea, which is why learning the topic beats memorising past questions. All repeated ideas

Every question

Human Genome Project questions, year by year

The opening words of each question as it appeared in the official paper, with the idea it tested.

NEET 20251 question

Q106
Which chromosome in the human genome has the highest number of genes?
Idea: Salient Features of HGP
New ideaEasyOne-line MCQ

NEET 20231 question

Q104
Expressed Sequence Tags (ESTs) refers to
Idea: Definition of Expressed Sequence Tags
New ideaEasyOne-line MCQ

NEET 20222 questions

Q113
DNA polymorphism forms the basis of :
Idea: DNA Polymorphism
New ideaEasyOne-line MCQ
Q140
If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different…
Idea: Sequence Annotation Definition
New ideaEasyOne-line MCQ

NEET 20211 question

Q144
DNA fingerprinting involves identifying differences in some specific regions in DNA sequence, called as :
Idea: DNA Fingerprinting and VNTRs
New ideaMediumOne-line MCQ

NEET 20191 question

Q158
Expressed Sequence Tags (ESTs) refers to :
Idea: ESTs vs Sequence Annotation
New ideaMediumOne-line MCQ

Questions from the official NEET UG papers published by NTA (CBSE before 2019). Topic and idea tags, counts and notes are Lumi’s.