NEET UG · Biology · Biomolecules

Biomolecule Structure: NEET previous year questions

33 questions in ten years of NEET, in 10 of 10 papers. Pattern: Every year. Here is how it is asked and which ideas come back.

Asked in 10 years: 33; about 3.1 per paper
Years asked: 10/10; last asked 2026
Chance of a question next paper: 93%; historical rate, how we compute it
Weighted estimate: 3.4; model; history: 3.1 a paper on average, typically 2–4

Key findings

01
Asked in 10 of 10 papers, 33 questions in all: #1 of 204 topics by ten-year total.
02
77% of its questions since 2018 tested an idea never asked before; 2 repeated an idea from the year before.
03
The most repeated idea is Enzyme Prosthetic Groups, asked 3 times (2019, 2024, 2025), usually as “statement i/ii on enzyme components”.
04
NEET has asked 19 of the 79 ideas in this topic; 41 have never been asked, directly or indirectly.
05
Mostly asked as one-line MCQ (61%); 64% easy, 0% hard, and up from 2.8 to 3.8 questions a paper since 2024.

Questions per year

Up to 2023: 2.8; per paper
Since 2024: 3.8; +1.0
Usual gap: 1.0 yrs; between papers asking it
Swing: ±1.3; questions, year to year

Recent framings

order/ranking of property
match list on biomolecules and functions
definition recall

Revise first

Function of GLUT-4 (2024 2026); Enzyme Prosthetic Groups (2019 2024 2025); Temperature and Competitive Inhibition (2023 2024)

How it is asked

Difficulty, format and skill

Across all 33 questions on Biomolecule Structure since 2017.

Difficulty

QUESTIONS

2112

Easy21 · 64%
Medium12 · 36%
Hard0 · 0%

Format

One-line MCQ · 20 Q61%
Match the lists · 7 Q21%
Other · 3 Q9%
Two statements · 3 Q9%

Skill tested

Recall · 25 Q76%
Concept · 6 Q18%
Calculation · 1 Q3%
Application · 1 Q3%

Repeats

New idea, or one asked before?

Each column is a paper. Blue questions tested an idea NEET had not asked before; navy ones went back to an idea from an earlier paper. 2017 is the first paper, so everything in it counts as new.

’17’18’19’20’21’22’23’24’25’26

Idea asked for the first time
Idea asked in an earlier paper

Coverage of the topic

NEET has asked 19 of the 79 ideas in this topic. 41 have never been asked yet.

191941

Asked directly19 · 24%
Touched inside another question19 · 24%
Never asked41 · 52%

Ideas come from Lumi’s syllabus map of NCERT. A never-asked idea is not a safe skip: most new questions come from exactly these.

Drill down

Idea, year, question

Every idea NEET tested in this topic, with its ten papers. Open one to read the questions.

ideaAskedShareYears’17’18’19’20’21’22’23’24’25’26

Repeated3 · 9%9%3/10
- 2025 · Q131
  Which one of the following enzymes contains 'Haem' as the prosthetic group?
  mediumOne-line MCQAsked the year before
- 2024 · Q119
  The cofactor of the enzyme carboxypeptidase is:
  easyOne-line MCQ
- 2019 · Q114
  Consider the following statements : (A) Coenzyme or metal ion that is tightly bound to enzyme protein is called prosthetic group. (B) A…
  mediumTwo statementsNew idea
Repeated3 · 9%9%2/102
Repeated2 · 6%6%2/10
Repeated2 · 6%6%2/10
Repeated2 · 6%6%2/10
Repeated2 · 6%6%2/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10
1 · 3%3%1/10

Squares are the ten papers, 2017 to 2026; darker means more questions. Share is of the level above.

Ideas

Every idea inside this topic

25 different ideas were tested; 6 came more than once. Glycosidic Linkages is the foundation for 14 other ideas in the syllabus.

Enzyme Prosthetic Groups3×
statement i/ii on enzyme components
One-line MCQ · 11% next
Temperature and Competitive Inhibition3×
identify enzyme inhibited by an inhibitor
One-line MCQ · 6% next
Function of GLUT-42×
match list on proteins and functions
Match the lists · 11% next
Holoenzyme Components2×
true statement selection on enzymes
One-line MCQ · 6% next · foundation for 2
Peptide Bond Formation2×
match list on biomolecule bonds
Match the lists · 6% next · foundation for 11
Glycosidic Linkages2×
identify substances with given bond types
One-line MCQ · 6% next · foundation for 14
Elemental Composition of the Body1×
order/ranking of property
One-line MCQ · 6% next
Nucleoside vs Nucleotide1×
match list on biomolecules and functions
Match the lists · 6% next
Six Classes of Enzymes1×
identify enzyme class from reaction
One-line MCQ · 6% next
Catalytic Cycle of an Enzyme1×
order of steps in a process
Other · 6% next
Phospholipid Structure and Lecithin1×
identify class of a biomolecule
One-line MCQ · 6% next
Cellulose Iodine Test Failure1×
reason for a chemical observation
One-line MCQ · 4% next
Polypeptide Chain Terminals1×
statement i/ii on protein structure
Two statements · 4% next
Biological Roles of Biomolecules1×
match list on biomolecules and functions
Match the lists · 4% next
Chitin Structure and Composition1×
identify composition of a structure
One-line MCQ · 4% next
Lipid Structure and Esters1×
count correct statements on lipids
Other · 4% next · foundation for 9
Fatty Acid Carbon Counting1×
count correct statements on lipids
Other · 4% next
Primary vs. Secondary Metabolites1×
identify examples of secondary metabolites
One-line MCQ · 4% next · foundation for 7
Secondary Metabolites: Toxins and Lectins1×
incorrectly paired example and class
One-line MCQ · 4% next
Acidic and Basic Amino Acids1×
identify amino acid of a given class
One-line MCQ · 4% next
Most Abundant Proteins1×
identify most abundant biomolecule
One-line MCQ · 4% next
Toxin Secondary Metabolites1×
match list on biomolecule functions
Match the lists · 4% next
Lectin Secondary Metabolites1×
classify example of a type
One-line MCQ · 4% next
Functional Groups of Sugars1×
definition recall
One-line MCQ · 4% next
Lipids in Acid-Insoluble Pool1×
odd-one-out among biomolecules
One-line MCQ · 4% next

Idea	Times	Format	Chance next	Foundation for
Enzyme Prosthetic Groupsstatement i/ii on enzyme components	3	One-line MCQRecall	11%	–
Temperature and Competitive Inhibitionidentify enzyme inhibited by an inhibitor	3	One-line MCQConcept	6%	–
Function of GLUT-4match list on proteins and functions	2	Match the listsRecall	11%	–
Holoenzyme Componentstrue statement selection on enzymes	2	One-line MCQRecall	6%	2 ideas
Peptide Bond Formationmatch list on biomolecule bonds	2	Match the listsRecall	6%	11 ideas
Glycosidic Linkagesidentify substances with given bond types	2	One-line MCQApplication	6%	14 ideas
Elemental Composition of the Bodyorder/ranking of property	1	One-line MCQRecall	6%	–
Nucleoside vs Nucleotidematch list on biomolecules and functions	1	Match the listsRecall	6%	–
Six Classes of Enzymesidentify enzyme class from reaction	1	One-line MCQRecall	6%	–
Catalytic Cycle of an Enzymeorder of steps in a process	1	OtherConcept	6%	–
Phospholipid Structure and Lecithinidentify class of a biomolecule	1	One-line MCQRecall	6%	–
Cellulose Iodine Test Failurereason for a chemical observation	1	One-line MCQConcept	4%	–
Polypeptide Chain Terminalsstatement i/ii on protein structure	1	Two statementsRecall	4%	–
Biological Roles of Biomoleculesmatch list on biomolecules and functions	1	Match the listsRecall	4%	–
Chitin Structure and Compositionidentify composition of a structure	1	One-line MCQRecall	4%	–
Lipid Structure and Esterscount correct statements on lipids	1	OtherConcept	4%	9 ideas
Fatty Acid Carbon Countingcount correct statements on lipids	1	OtherRecall	4%	–
Primary vs. Secondary Metabolitesidentify examples of secondary metabolites	1	One-line MCQRecall	4%	7 ideas
Secondary Metabolites: Toxins and Lectinsincorrectly paired example and class	1	One-line MCQRecall	4%	–
Acidic and Basic Amino Acidsidentify amino acid of a given class	1	One-line MCQRecall	4%	–
Most Abundant Proteinsidentify most abundant biomolecule	1	One-line MCQRecall	4%	–
Toxin Secondary Metabolitesmatch list on biomolecule functions	1	Match the listsRecall	4%	–
Lectin Secondary Metabolitesclassify example of a type	1	One-line MCQRecall	4%	–
Functional Groups of Sugarsdefinition recall	1	One-line MCQRecall	4%	–
Lipids in Acid-Insoluble Poolodd-one-out among biomolecules	1	One-line MCQRecall	4%	–

Chance next is the historical rate at which an idea with this record came back in the following paper. It is low for every idea, which is why learning the topic beats memorising past questions. All repeated ideas

Every question

Biomolecule Structure questions, year by year

The opening words of each question as it appeared in the official paper, with the idea it tested.

NEET 20262 questions

Q106
Match List-I with List-II. List-I | List-II A. Starch | I. Fights infection B. Antibody | II. Energy storage C. Concanavalin A | III.…
Idea: Function of GLUT-4
MediumMatch the lists
Q134
Arrange the following elements in descending order of their contribution to percentage weight of the human body. (a) Oxygen | (b) Carbon…
Idea: Elemental Composition of the Body
New ideaMediumOne-line MCQ

NEET 20254 questions

Q117
Name the class of enzyme that usually catalyze the following reaction : $S - G + S^\# \to S + S^\# - G$ Where, G $\to$ a group other than…
Idea: Six Classes of Enzymes
New ideaMediumOne-line MCQ
Q131
Which one of the following enzymes contains 'Haem' as the prosthetic group?
Idea: Enzyme Prosthetic Groups
Asked last yearMediumOne-line MCQ
Q137
Match List I with List II. List I | List II A. Adenosine | I. Nitrogen base B. Adenylic acid | II. Nucleotide C. Adenine | III. Nucleoside…
Idea: Nucleoside vs Nucleotide
New ideaEasyMatch the lists
Q149
The protein portion of an enzyme is called :
Idea: Holoenzyme Components
EasyOne-line MCQ

NEET 20246 questions

Q109
Lecithin, a small molecular weight organic compound found in living tissues, is an example of:
Idea: Phospholipid Structure and Lecithin
New ideaEasyOne-line MCQ
Q119
The cofactor of the enzyme carboxypeptidase is:
Idea: Enzyme Prosthetic Groups
EasyOne-line MCQ
Q127
Inhibition of Succinic dehydrogenase enzyme by malonate is a classical example of:
Idea: Temperature and Competitive Inhibition
Asked last yearEasyOne-line MCQ
Q144
Match List I with List II List I | List II A. GLUT-4 | I. Hormone B. Insulin | II. Enzyme C. Trypsin | III. Intercellular ground substance…
Idea: Function of GLUT-4
New ideaMediumMatch the lists
Q170
Match List I with List II List-I | List-II A. Lipase | I. Peptide bond B. Nuclease | II. Ester bond C. Protease | III. Glycosidic bond D.…
Idea: Peptide Bond Formation
EasyMatch the lists
Q187
Regarding catalytic cycle of an enzyme action, select the correct sequential steps: A. Substrate enzyme complex formation. B. Free enzyme…
Idea: Catalytic Cycle of an Enzyme
New ideaMediumOther

NEET 20234 questions

Q102
Cellulose does not form blue colour with Iodine because
Idea: Cellulose Iodine Test Failure
New ideaEasyOne-line MCQ
Q149
Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of
Idea: Temperature and Competitive Inhibition
New ideaMediumOne-line MCQ
Q166
Given below are two statements: Statement I: Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature…
Idea: Temperature and Competitive Inhibition
New ideaEasyTwo statements
Q172
Given below are two statements: Statement I: A protein is imagined as a line, the left end represented by first amino acid (C-terminal)…
Idea: Polypeptide Chain Terminals
New ideaEasyTwo statements

NEET 20224 questions

Q134
Exoskeleton of arthropods is composed of :
Idea: Chitin Structure and Composition
New ideaEasyOne-line MCQ
Q138
Read the following statements on lipids and find out correct set of statements : (a) Lecithin found in the plasma membrane is a glycolipid…
Idea: Lipid Structure and Esters
New ideaMediumOther
Q160
A dehydration reaction links two glucose molecules to produce maltose. If the formula for glucose is $\mathrm{C_6H_{12}O_6}$ then what is…
Idea: Glycosidic Linkages
EasyOne-line MCQ
Q194
Match List - I with List - II. List - I (Biological Molecules) | List - II (Biological functions) (a) Glycogen | (i) Hormone (b) Globulin…
Idea: Biological Roles of Biomolecules
New ideaEasyMatch the lists

NEET 20214 questions

Q113
Which of the following are not secondary metabolites in plants ?
Idea: Primary vs. Secondary Metabolites
New ideaEasyOne-line MCQ
Q142
Match List - I with List - II. List - I | List - II (a) Protein | (i) C = C double bonds (b) Unsaturated fatty acid | (ii) Phosphodiester…
Idea: Peptide Bond Formation
New ideaEasyMatch the lists
Q158
Identify the incorrect pair.
Idea: Secondary Metabolites: Toxins and Lectins
New ideaMediumOne-line MCQ
Q192
Following are the statements with reference to 'lipids'. (a) Lipids having only single bonds are called unsaturated fatty acids. (b)…
Idea: Fatty Acid Carbon Counting
New ideaMediumOther

NEET 20204 questions

Q11
Identify the substances having glycosidic bond and peptide bond, respectively in their structure :
Idea: Glycosidic Linkages
New ideaEasyOne-line MCQ
Q30
Match the following : (a) Inhibitor of catalytic activity | (i) Ricin (b) Possess peptide bonds | (ii) Malonate (c) Cell wall material in…
Idea: Toxin Secondary Metabolites
New ideaMediumMatch the lists
Q79
Identify the basic amino acid from the following.
Idea: Acidic and Basic Amino Acids
New ideaEasyOne-line MCQ
Q82
Which one of the following is the most abundant protein in the animals ?
Idea: Most Abundant Proteins
New ideaEasyOne-line MCQ

NEET 20192 questions

Q112
Concanavalin A is :
Idea: Lectin Secondary Metabolites
New ideaEasyOne-line MCQ
Q114
Consider the following statements : (A) Coenzyme or metal ion that is tightly bound to enzyme protein is called prosthetic group. (B) A…
Idea: Enzyme Prosthetic Groups
New ideaMediumTwo statements

NEET 20181 question

Q117
The two functional groups characteristic of sugars are
Idea: Functional Groups of Sugars
New ideaEasyOne-line MCQ

NEET 20172 questions

Q103
Which one of the following statements is correct with reference to enzymes ?
Idea: Holoenzyme Components
EasyOne-line MCQ
Q105
Which of the following are not polymeric ?
Idea: Lipids in Acid-Insoluble Pool
EasyOne-line MCQ

Questions from the official NEET UG papers published by NTA (CBSE before 2019). Topic and idea tags, counts and notes are Lumi’s.